The Journal of Organic Chemistry

N, 2-Dilithioalkylamines from aziridines by naphthalene-catalyzed reductive opening. Synthetic applications

J Almena, F Foubelo, M Yus

Index: Almena, Juan; Foubelo, Francisco; Yus, Miguel Journal of Organic Chemistry, 1994 , vol. 59, # 11 p. 3210 - 3215

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Citation Number: 70

Abstract

Functionalized organolithium compounds' are interesting intermediates in preparative organic chemistry because their reactions with electrophilic reagents lead directly to polyfunctionalized molecules. The stability of these organolithium reagents depends strongly on three factors:(a) the hybridization of the carbon atom that bears the lithium atom;(b) the compatibility of the functionality and the carbon-lithium bond, and (c) the ...

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