2-(Pyrrolidin-1-yl) ethyl-3, 4-dihydroisoquinolin-1 (2H)-one Derivatives as Potent and Selective Histamine-3 Receptor Antagonists
D Zhou, JL Gross, AB Adedoyin…
Index: Journal of Medicinal Chemistry, , vol. 55, # 5 p. 2452 - 2468
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Citation Number: 5
Abstract
... Journal of Medicinal Chemistry. ... An alternative approach to biaryl lactam compounds 18–23 is shown in Scheme 2. The chemistry was designed to install different cyclic amines via reductive amination as a penultimate step. ...
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