A high throughput synthesis of aryl triflate and aryl nonaflate promoted by a polymer supported base (PTBD)
S Boisnard, J Chastanet, J Zhu
Index: Boisnard, Sabine; Chastanet, Jaqueline; Zhu, Jieping Tetrahedron Letters, 1999 , vol. 40, # 42 p. 7469 - 7472
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Citation Number: 27
Abstract
A rapid synthesis of aryl nonaflate was developed using 4-nitrophenyl triflate and 4- nitrophenyl nonaflate as perfluoroalkanesulfonyl transfer reagents in combination with a polymer supported base (PTBD). Simple filtration of the reaction mixture gave the desired products in high chemical yields and purity. The unique role of PTBD as a base and side product scavenger was demonstrated.
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