An Efficient, Scalable Process for Benzphetamine Hydrochloride

C Pramanik, K Bapat, A Chaudhari…

Index: Marco, Jose L.; Royer, Jacques; Husson, Henri-Philippe Synthetic Communications, 1987 , vol. 17, # 6 p. 669 - 676

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Abstract

... figure Scheme 2. The synthetic sequence was repeated and found to be reproducible on 500-g scale. ... The free base was then dissolved in ethyl acetate (6 L) and cooled to 5–10 °C, and to this was added ethyl acetate HCl (32 L, 8–10%), and the ... The injection volume was 20 μL. ...

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