An improved synthesis of (E)-cinnamic acid derivatives via the Claisen–Schmidt condensation
M Hatsuda, T Kuroda, M Seki
Index: Hatsuda, Masanori; Kuroda, Tooru; Seki, Masahiko Synthetic Communications, 2003 , vol. 33, # 3 p. 427 - 434
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Citation Number: 25
Abstract
A variety of (E)-cinnamic acid derivatives are prepared in high yields through the Claisen–Schmidt condensation in the presence of sodium metal and a catalytic amount of methanol with toluene employed as the co-solvent. ... A variety of (E)-cinnamic acid derivatives are prepared in high yields through the Claisen–Schmidt condensation in the presence of sodium metal and a catalytic amount of methanol with toluene employed as the co-solvent.
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