2, 3-Disubstituted indoles from olefins and hydrazines via tandem hydroformylation–Fischer indole synthesis and skeletal rearrangement

P Linnepe, AM Schmidt, P Eilbracht

Index: Schmidt, Axel M.; Eilbracht, Peter Organic and Biomolecular Chemistry, 2005 , vol. 3, # 12 p. 2333 - 2343

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Citation Number: 59

Abstract

The tandem hydroformylation–Fischer indolisation protocol is used in the synthesis of 2, 3- disubstituted indoles. After hydroformylation of selected olefins to form α-branched aldehydes in a one-pot procedure these are condensed with phenylhydrazine to give

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