A one step synthesis of 1, 4-benzodiazepines: synthetic studies on neothramycin
M Mori, M Kimura, Y Uozumi, Y Ban
Index: Mori, Miwako; Kimura, Masaya; Uozumi, Yasuhiro; Ban, Yoshio Tetrahedron Letters, 1985 , vol. 26, # 48 p. 5947 - 5950
Full Text: HTML
Citation Number: 33
Abstract
Abstract A one step synthesis of 1, 4-benzodiazepines from o-haloanilines and amino acids was achieved by use of palladium catalyzed carbonylation, by which application a synthesis of the model compounds (23a and 23b) of Neothramycin (A and B) was described. An efficient chemoselective reduction of the amide was provided.
Related Articles:
Eco-friendly synthesis of 1, 4-benzodiazepine-2, 5-diones in the ionic liquid [bmim] Br
[Jadidi, Khosrow; Ghahremanzadeh, Ramin; Asgari, Davoud; Eslami, Parisa; Arvin-Nezhad, Hamid Monatshefte fur Chemie, 2008 , vol. 139, # 10 p. 1229 - 1232]
New Routes to 1, 4-benzodiazepin-2, 5-diones
[Akssira; Boumzebra; Kasmi; Dahdouh; Roumestant; Viallefont Tetrahedron, 1994 , vol. 50, # 30 p. 9051 - 9060]
[Ishikura, Minoru; Mori, Miwako; Ikeda, Toshihito; Terashima, Masanao; Ban, Yoshio Journal of Organic Chemistry, 1982 , vol. 47, # 12 p. 2456 - 2461]
[Ishikura, Minoru; Mori, Miwako; Ikeda, Toshihito; Terashima, Masanao; Ban, Yoshio Journal of Organic Chemistry, 1982 , vol. 47, # 12 p. 2456 - 2461]
[Ishikura, Minoru; Mori, Miwako; Ikeda, Toshihito; Terashima, Masanao; Ban, Yoshio Journal of Organic Chemistry, 1982 , vol. 47, # 12 p. 2456 - 2461]