A general and efficient protocol for the synthesis of biaryl ethers from aryl silyl ethers using Cs2CO3
SL Cui, ZY Jiang, YG Wang
Index: Cui, Sun-Liang; Jiang, Zhi-Yong; Wang, Yan-Guang Synlett, 2004 , # 10 p. 1829 - 1831
Full Text: HTML
Citation Number: 4
Abstract
Abstract A general and efficient one-step procedure has been developed for the synthesis of biaryl ethers via direct coupling of electron-deficient arylhalides or aryl triflates to aryl t- butyldimethyl-silyl (TBS) ethers using Cs 2 CO 3. The protocol was also applied to electron- rich arylhalides by addition of a catalytic amount of copper (I) iodide. The reaction is rapid and provides good to excellent yields.
Related Articles:
Ligand-free copper-catalyzed O-arylation of nitroarenes with phenols
[Chen, Jiuxi; Wang, Xingyong; Zheng, Xingwang; Ding, Jinchang; Liu, Miaochang; Wu, Huayue Tetrahedron, 2012 , vol. 68, # 43 p. 8905 - 8907]
[Zhang, Ying-Peng; Jiao, Ya-Cong; Yang, Yun-Shang; Li, Chun-Lei Tetrahedron Letters, 2013 , vol. 54, # 48 p. 6494 - 6497]
Palladium-Catalyzed Decarboxylative Coupling of Isatoic Anhydrides with Arylboronic Acids
[Zheng, Xingwang; Ding, Jinchang; Chen, Jiuxi; Gao, Wenxiao; Liu, Miaochang; Wu, Huayue Organic Letters, 2011 , vol. 13, # 7 p. 1726 - 1729]
[Dimmock, Jonathan R.; Puthucode, Ramanan N.; Smith, Jennifer M.; Hetherington, Mark; Quail, J. Wilson; Pugazhenthi, Uma; Lechler, Terry; Stables, James P. Journal of Medicinal Chemistry, 1996 , vol. 39, # 20 p. 3984 - 3997]
Synthesis of l, l-isodityrosine
[Boger, Dale L.; Yohannes, Daniel Tetrahedron Letters, 1989 , vol. 30, # 16 p. 2053 - 2056]