A new solvent-free synthesis of α, β-unsaturated ketones from acetals with aryl ketones under microwave irradiation

D Huang, JX Wang, Y Hu, Y Zhang…

Index: Huang, Danfeng; Wang, Jin-Xian; Hu, Yulai; Zhang, Yumei; Tang, Jing Synthetic Communications, 2002 , vol. 32, # 7 p. 971 - 979

Full Text: HTML

Citation Number: 25

Abstract

ABSTRACT A new, rapid and efficient method for the synthesis of α, β-unsaturated ketones under microwave irradiation conditions is described. The process involves the reaction of acetals with aryl ketones in the absence of solvent using Lewis acids as catalysts under microwave irradiation to afford the α, β-unsaturated ketones in good to excellent isolated yields. The reaction mechanism is briefly discussed.

Related Articles:

Nanocrystalline MgO for asymmetric Henry and Michael reactions

[Choudary, Boyapati M.; Kantam, Mannepalli L.; Ranganath, Kalluri V. S.; Mahendar, Koosam; Sreedhar, Bojja Journal of the American Chemical Society, 2004 , vol. 126, # 11 p. 3396 - 3397]

Palladium-catalyzed and copper-mediated cross-coupling reaction of aryl-or alkenylboronic acids with acid chlorides under neutral conditions: efficient synthetic …

[Ogawa, Daisuke; Hyodo, Keita; Suetsugu, Masato; Li, Jing; Inoue, Yoshiaki; Fujisawa, Mamoru; Iwasaki, Masayuki; Takagi, Kentaro; Nishihara, Yasushi Tetrahedron, 2013 , vol. 69, # 12 p. 2565 - 2571]

A palladium catalyzed atom-efficient cross-coupling reactivity of triarylbismuths with α, β-unsaturated acyl chlorides

[Rao, Maddali L.N.; Venkatesh, Varadhachari; Jadhav, Deepak N. Journal of Organometallic Chemistry, 2008 , vol. 693, # 15 p. 2494 - 2498]

The surfactant-promoted cross-coupling reactions of arylboronic acids with carboxylic anhydrides or acyl chlorides in water

[Xin, Bingwei; Zhang, Yuhong; Cheng, Kai Synthesis, 2007 , # 13 p. 1970 - 1978]

Continuous-flow hydration–condensation reaction: Synthesis of α, β-unsaturated ketones from alkynes and aldehydes by using a heterogeneous solid acid …

[Rueping, Magnus; Bootwicha, Teerawut; Baars, Hannah; Sugiono, Erli Beilstein Journal of Organic Chemistry, 2011 , vol. 7, p. 1680 - 1687]

More Articles...