Ti??Catalyzed Barbier??Type Allylations and Related Reactions

…, M Paradas, D Choquesillo??Lazarte…

Index: Estevez, Rosa E.; Justicia, Jose; Bazdi, Btissam; Fuentes, Noelia; Paradas, Miguel; Choquesillo-Lazarte, Duane; Garcia-Ruiz, Juan M.; Robles, Rafael; Gansaeuer, Andreas; Cuerva, Juan M.; Oltra, J. Enrique Chemistry - A European Journal, 2009 , vol. 15, # 12 p. 2774 - 2791

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Citation Number: 44

Abstract

Abstract Versatility of titanium: Titanocene (III) complexes catalyze Barbier-type allylations, intramolecular crotylations (cyclizations), and prenylations of a wide range of aldehydes and ketones. These reactions take place at RT under mild conditions compatible with many functional groups; provide good yields of open-chain and cyclic homoallylic alcohols, including heterocyclic derivatives; and can be conducted enantioselectively by using ...

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