Regioselective hydrostannation of diarylalkynes directed by a labile ortho bromine atom: An easy access to stereodefined triarylolefins, hybrids of combretastatin A-4 …
E Rasolofonjatovo, O Provot, A Hamze, J Bignon…
Index: Rasolofonjatovo, Evelia; Provot, Olivier; Hamze, Abdallah; Bignon, Jerome; Thoret, Sylviane; Brion, Jean-Daniel; Alami, Mouad European Journal of Medicinal Chemistry, 2010 , vol. 45, # 9 p. 3617 - 3626
Full Text: HTML
Citation Number: 18
Abstract
A series of triarylolefins bearing the combretastatin A-4 and the isocombretastatin A-4 cores were synthesized and evaluated. The cooperative ortho-effect of a labile bromine atom in the regioselective hydrostannation of unsymmetrical diarylalkynes leading to stereodefined triarylolefins is presented.
Related Articles:
[Lv, Jun; Liu, Qiancai; Tang, Jie; Perdih, Franc; Kranjc, Kristof Tetrahedron Letters, 2012 , vol. 53, # 39 p. 5248 - 5252]
[Lv, Jun; Liu, Qiancai; Tang, Jie; Perdih, Franc; Kranjc, Kristof Tetrahedron Letters, 2012 , vol. 53, # 39 p. 5248 - 5252]