Tetrahedron Letters

A facile synthesis of indolo [3, 2, 1-jk] carbazoles via palladium-catalyzed intramolecular cyclization

J Lv, Q Liu, J Tang, F Perdih, K Kranjc

Index: Lv, Jun; Liu, Qiancai; Tang, Jie; Perdih, Franc; Kranjc, Kristof Tetrahedron Letters, 2012 , vol. 53, # 39 p. 5248 - 5252

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Citation Number: 13

Abstract

A new efficient synthesis of indolo [3, 2, 1-jk] carbazoles by the palladium-catalyzed cyclization of N-(2-bromoaryl) carbazoles is described. The reaction involves intramolecular C–C bond formation, coupled with the cleavage of a C–X bond and a C–H bond on carbazole ring. Substitutions on N-aryl core with either electron-donating or electron- withdrawing groups are introduced, and different reaction factors for cyclization are ...