Molecules

Efficient one-pot synthesis of 5-chloromethylfurfural (CMF) from carbohydrates in mild biphasic systems

…, Y Li, Z Xiang, K Chen, R Yang, DS Argyropoulos

Index: Gao, Wenhua; Li, Yiqun; Xiang, Zhouyang; Chen, Kefu; Yang, Rendang; Argyropoulos, Dimitris S. Molecules, 2013 , vol. 18, # 7 p. 7675 - 7685

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Citation Number: 11

Abstract

Abstract: 5-Halomethylfurfurals can be considered as platform chemicals of high reactivity making them useful for the preparation of a variety of important compounds. In this study, a one-pot route for the conversion of carbohydrates into 5-chloromethylfurfural (CMF) in a simple and efficient (HCl-H 3 PO 4/CHCl 3) biphasic system has been investigated. Monosaccharides such as D-fructose, D-glucose and sorbose, disaccharides such as ...

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