Total synthesis of naturally occurring furan compounds 5-{[(4-hydroxybenzyl) oxy] methyl}-2-furaldehyde and pichiafuran C

H Quiroz-Florentino, RI Hernández-Benitez…

Index: Quiroz-Florentino, Hector; Hernandez-Benitez, R. Israel; Avina, Judit A.; Burgueno-Tapia, Eleuterio; Tamariz, Joaquin Synthesis, 2011 , # 7 p. 1106 - 1112

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Citation Number: 4

Abstract

Abstract The synthesis of the natural furan derivatives 5-{[(4-hydroxybenzyl) oxy] methyl}-2- furaldehyde and pichiafuran C is described. Diverse alternative synthetic approaches were developed for the preparation of these natural products. They were prepared through an etherification reaction of the key furan precursor 5-(hydroxymethyl)-2-furaldehyde (HMF), which can be readily obtained from d-fructose, d-glucose, or sucrose, with the ...