Oxidation of fluoroalkyl-substituted carbinols by the Dess-Martin reagent
RJ Linderman, DM Graves
Index: Linderman, Russell J.; Graves, David M. Journal of Organic Chemistry, 1989 , vol. 54, # 3 p. 661 - 668
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Citation Number: 132
Abstract
During our initial investigations into this problem, we had two goals in mind, an oxidation procedure, which would occur under mild reaction conditions without requiring a large excess (10-15 equiv) of oxidant, and a reproducible procedure, which would be applicable to a variety of functionalized fluoroalkyl-substituted carbinols. Given the potential application of this chemistry to the synthesis of enzyme inhibitors, we chose to survey oxidants that ...
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