Acylation of α-fluorophosphonoacetate derivatives using magnesium chloride-triethylamine
DY Kim, YM Lee, YJ Choi
Index: Kim, Dae Young; Lee, Yong Mi; Choi, Young Jae Tetrahedron, 1999 , vol. 55, # 45 p. 12983 - 12990
Full Text: HTML
Citation Number: 14
Abstract
Acylation of α-fluorophosphonoacetate derivatives in the presence of magnesium chloride- triethylamine has been described. Acylations of triethyl α-fluorophosphonoacetate 1 and diethyl α-fluorophosphonoacetic acid 7 were proceeded under mild conditions to provide α- fluoro-β-keto esters 3 and α-fluoro-β-keto phosphonates 9, respectively, in high yields.
Related Articles:
[Engman, Mattias; Diesen, Jarle S.; Paptchikhine, Alexander; Andersson, Pher G. Journal of the American Chemical Society, 2007 , vol. 129, # 15 p. 4536 - 4537]
Oxidation of fluoroalkyl-substituted carbinols by the Dess-Martin reagent
[Linderman, Russell J.; Graves, David M. Journal of Organic Chemistry, 1989 , vol. 54, # 3 p. 661 - 668]
[Thenappan, Alagappan; Burton, Donald J. Journal of Organic Chemistry, 1991 , vol. 56, # 1 p. 273 - 277]