Synthesis of resveratrol using a direct decarbonylative Heck approach from resorcylic acid
MB Andrus, J Liu, EL Meredith, E Nartey
Index: Andrus, Merritt B.; Liu, Jing; Meredith, Erik L.; Nartey, Edward Tetrahedron Letters, 2003 , vol. 44, # 26 p. 4819 - 4822
Full Text: HTML
Citation Number: 92
Abstract
The phytoalexin resveratrol has been made using a decarbonylative Heck reaction. The acid chloride derived from 3, 5-dihydroxybenzoic acid was coupled with 4-acetoxystyrene in the presence of palladium acetate and N, N-bis-(2, 6-diisopropylphenyl) dihydroimidazolium chloride to give the substituted stilbene in 73% yield as the key step.
Related Articles:
A new efficient resveratrol synthesis
[Guiso, Marcella; Marra, Carolina; Farina, Angela Tetrahedron Letters, 2002 , vol. 43, # 4 p. 597 - 598]
A new efficient resveratrol synthesis
[Guiso, Marcella; Marra, Carolina; Farina, Angela Tetrahedron Letters, 2002 , vol. 43, # 4 p. 597 - 598]
A new efficient resveratrol synthesis
[Guiso, Marcella; Marra, Carolina; Farina, Angela Tetrahedron Letters, 2002 , vol. 43, # 4 p. 597 - 598]
Selective esterification of the polyphenol resveratrol at the 4′-position
[Acerson, Mark J.; Andrus, Merritt B. Tetrahedron Letters, 2014 , vol. 55, # 3 p. 757 - 760]