Tetrahedron Letters

Radical additions to allyl bromides. A synthetically useful,'Tin-Free'method for carbon–carbon bond formation

JA Struss, M Sadeghipour, JM Tanko

Index: Struss, John A.; Sadeghipour, Mitra; Tanko, James M. Tetrahedron Letters, 2009 , vol. 50, # 18 p. 2119 - 2120

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Citation Number: 17

Abstract

The scope and limitations of a novel free radical chain process involving the addition of benzyl radicals to substituted allyl bromides were examined and extended to explore the effect of α-substitution on the allyl bromide (R′), and the use of pyrrolidine amides and oxazolidinone as activating substituents (Z) as the first steps toward the development of a stereoselective, radical-based C–C bond-forming reaction which is environmentally ...

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