Structure-based design of 7-azaindole-pyrrolidine amides as inhibitors of 11β-hydroxysteroid dehydrogenase type I

E Valeur, S Christmann-Franck, F Lepifre…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 18 p. 5909 - 5914

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Citation Number: 9

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... 8 Many efforts towards the discovery and development of 11β-HSD1 inhibitors have been carried out, and led to the discovery of several chemical classes, that could be mainly grouped (based on the fragment interacting with the ...