Aminopyrazoles with high affinity for the human neuropeptide Y5 receptor

CP Kordik, C Luo, BC Zanoni, SL Dax…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 17 p. 2283 - 2286

Full Text: HTML

Citation Number: 29

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... Replacement of the sulfonamido group with either an amide (48) or a reverse amide (49) resulted in a loss of activity, indicating that the sulfonamide is critical for activity here as it is for some of the other NPY Y5 chemical series, as ...

Related Articles:

Tyrphostins. II. Heterocyclic and. alpha.-substituted benzylidenemalononitrile tyrphostins as potent inhibitors of EGF receptor and ErbB2/neu tyrosine kinases

[Journal of Medicinal Chemistry, , vol. 34, # 6 p. 1896 - 1907]

Allosteric modulation of the adenosine A1 receptor. Synthesis and biological evaluation of novel 2-amino-3-benzoylthiophenes as allosteric enhancers of agonist …

[Journal of Medicinal Chemistry, , vol. 42, # 18 p. 3629 - 3635]

Tyrphostins. II. Heterocyclic and. alpha.-substituted benzylidenemalononitrile tyrphostins as potent inhibitors of EGF receptor and ErbB2/neu tyrosine kinases

[Journal of Medicinal Chemistry, , vol. 34, # 6 p. 1896 - 1907]

An efficient method for synthesis of phenacyl derivatives under homogeneous phase transfer catalyst condition in aqueous media

[Chinese Chemical Letters, , vol. 22, # 3 p. 300 - 302]

Synthesis and biological evaluation of 3-aryl-quinoxaline-2-carbonitrile 1, 4-di-N-oxide derivatives as hypoxic selective anti-tumor agents

[Molecules, , vol. 17, # 8 p. 9683 - 9696]

More Articles...