Manganese??Catalyzed Cleavage of a Carbon–Carbon Single Bond between Carbonyl Carbon and α??Carbon Atoms of Ketones

Y Kuninobu, T Uesugi, A Kawata…

Index: Kuninobu, Yoichiro; Uesugi, Tadamasa; Kawata, Atsushi; Takai, Kazuhiko Angewandte Chemie - International Edition, 2011 , vol. 50, # 44 p. 10406 - 10408

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Citation Number: 48

Abstract

Olefin metathesis, which proceeds through a carbon–carbon (CÀC) double bond cleavage, is a well-known and useful method in synthetic organic chemistry.[1] In contrast, cleavage of a CÀC single bond is still one of the most difficult and challenging reactions in organic synthesis. Recently, there have been several reports on transition-metal-catalyzed transformations.[2] For example, reactions of strained molecules, such as three-and four- ...

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