An efficient approach to 1, 3, 5-tris-arylhexahydro-1, 3, 5-triazines

…, MS Morales-Ríos, P Joseph-Nathan

Index: Rivera, Augusto; Torres, Olga Lucia; Leiton, Jesus D.; Morales-Rios, Martha S.; Joseph-Nathan, Pedro Synthetic Communications, 2002 , vol. 32, # 9 p. 1407 - 1414

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Citation Number: 24

Abstract

ABSTRACT In this paper we report a facile and efficient procedure for the synthesis of 1, 3, 5- tris-arylhexahydro-1, 3, 5-triazines (3) by reaction of anilines 1 with 1, 3, 6, 8-tetrazatricyclo [4.4. 1.1 [3],[8a],[8b]-dodecane (TATD)(2). The diequatorial chair conformational preference of 3b (Ar= p-tolyl) in the solid state was established by X-ray crystallography and agrees well with molecular mechanics calculations.