Tetrahedron letters

Access to 4-substituted 3, 4-dihydroquinolin-2 (1H)-ones by an unusual radical cyclisation of a secondary amide

G Binot, SZ Zard

Index: Binot, Gregori; Zard, Samir Z. Tetrahedron Letters, 2005 , vol. 46, # 44 p. 7503 - 7506

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Citation Number: 29

Abstract

Development of new synthetic pathways to these compounds has thus recently attracted some attention from organic chemists, broadening the scope of substrates classically obtained by Friedländer-type methods or Friedel–Crafts cyclisations. 3 These new routes include, for instance, multi-component reactions, 4 palladium chemistry or rhodium catalysis. 5 In contrast, radical chemistry has not been considered in this context. 6 This is, in part, a ...

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