Effect of acyclic pyrimidines related to 9-[(1, 3-dihydroxy-2-propoxy) methyl] guanine on herpes viruses
LM Beauchamp, BL Serling, JE Kelsey…
Index: Beauchamp, Lilia M.; Serling, Barbara L.; Kelsey, John E.; Biron, Karen K.; Collins, Peter; et al. Journal of Medicinal Chemistry, 1988 , vol. 31, # 1 p. 144 - 149
Full Text: HTML
Citation Number: 89
Abstract
A series of pyrimidines related to the potent antiherpetic agent 9-[(1, 3-dihydroxy-2-propoxy) methyl] guanine(1, BW B759U), all containing the same acyclic chain, have been synthesized. Some of the compounds were derivatives of the naturally occurring bases, cytosine, uracil, and thymine; others included compounds in which the 5-position of the cytosine and uracil moieties were substituted by bromo, iodo, fluoro, methyl, and amino ...
Related Articles:
Photochemical and thermal reactions of 2-aryloxybenzohydroxamic acids
[Das, Vijay Kumar; Devi, Rashmi Rekha; Thakur, Ashim Jyoti Applied Catalysis A: General, 2013 , vol. 456, p. 118 - 125]
Electrochemical synthesis of amides: direct transformation of methyl ketones with formamides
[Huang, Haolai; Yuan, Gaoqing; Li, Xianwei; Jiang, Huanfeng Tetrahedron Letters, 2013 , vol. 54, # 52 p. 7156 - 7159]
[Zhang, Nana; Li, Binyao; Zhong, Hongban; Huang, Jianhui Organic and Biomolecular Chemistry, 2012 , vol. 10, # 47 p. 9429 - 9439]
[Friestad, Gregory K.; Ji, An Organic Letters, 2008 , vol. 10, # 11 p. 2311 - 2313]
[Friestad, Gregory K.; Ji, An Organic Letters, 2008 , vol. 10, # 11 p. 2311 - 2313]