Mn-mediated coupling of alkyl iodides and ketimines: A radical addition route to α, α-disubstituted α-aminoesters
GK Friestad, A Ji
Index: Friestad, Gregory K.; Ji, An Organic Letters, 2008 , vol. 10, # 11 p. 2311 - 2313
Full Text: HTML
Citation Number: 33
Abstract
We have addressed this problem by developing Mn-mediated coupling of alkyl iodides with N-acylhydrazones,(2) exploiting conditions of notable versatility with respect to both coupling components.(3) Until now, these Mn-mediated coupling reactions have been limited to aldehyde-derived imino acceptors. However, additions to ketone-derived imino compounds(4) are of particular interest as they could provide a diverse range of tert-alkyl ...
Related Articles:
Photochemical and thermal reactions of 2-aryloxybenzohydroxamic acids
[Das, Vijay Kumar; Devi, Rashmi Rekha; Thakur, Ashim Jyoti Applied Catalysis A: General, 2013 , vol. 456, p. 118 - 125]
Electrochemical synthesis of amides: direct transformation of methyl ketones with formamides
[Huang, Haolai; Yuan, Gaoqing; Li, Xianwei; Jiang, Huanfeng Tetrahedron Letters, 2013 , vol. 54, # 52 p. 7156 - 7159]
[Zhang, Nana; Li, Binyao; Zhong, Hongban; Huang, Jianhui Organic and Biomolecular Chemistry, 2012 , vol. 10, # 47 p. 9429 - 9439]
[Jo, Youngshin; Ju, Jinhun; Choe, Jaehoon; Kwang, Ho Song; Lee, Sunwoo Journal of Organic Chemistry, 2009 , vol. 74, # 16 p. 6358 - 6361]
[Beak, Peter; Basha, Anwer; Kokko, Bruce; Loo, DeKai Journal of the American Chemical Society, 1986 , vol. 108, # 19 p. 6016 - 6023]