An Aurone‐derived Low‐molecular‐weight Fluorescence Probe for the Detection of Hg2+ in Aqueous Solution and Living Cells

Min Zhang; Yong‐Tuan Bao; Wenbo Yang; Hui‐Feng Xiao; Zhi‐Xiang Han; Xiangyang Wu; Liuqing Yang

Index: 10.1002/jhet.3143

Full Text: HTML

Abstract

A low‐molecular‐weight fluorescent probe 1 (M.W. = 238.24) based on aurone was synthesized, and its application in fluorescent detection of Hg2+ in aqueous solution and living cells was reported. It exhibited an “on–off” fluorescent response toward Hg2+ in aqueous solution. Both the color and fluorescence changes of the probe were remarkably specific for Hg2+ in the presence of other common metal ions, satisfying the selective requirements for biomedical and environmental monitoring application. The probe has been applied in direct measurement of Hg2+ content in river water samples and imaging of Hg2+ in living cells, which further indicates the potential application values in environmental and biological systems.