UnyLinker: An efficient and scaleable synthesis of oligonucleotides utilizing a universal linker molecule: A novel approach to enhance the purity of drugs
VT Ravikumar, RK Kumar, P Olsen…
Index: Jankowska, Jadwiga; Stawinski, Jacek Synthesis, 1984 , # 5 p. 408 - 410
Full Text: HTML
Citation Number: 6
Abstract
... based on norbornylene (6), 5-norbornene-2-carboxylic acid (7), and 5-norbornene-2 ... We proposed 12 to be an optimally designed molecule for efficient synthesis of oligonucleotides. Thus, UnyLinker 12 was synthesized and loaded onto various solid supports and evaluated for ...
Related Articles:
2, 4-Dinitrophenol as an activating reagent in a facile preparation of cyclic phosphate triesters
[Amigues, Eric J.; Migaud, Marie E. Tetrahedron Letters, 2004 , vol. 45, # 5 p. 1001 - 1004]
A convenient synthesis of 6-, 7-, and 8-membered cyclic phosphodiesters
[Ramirez, Fausto; Tsuboi, Hikotada; Okazaki, Hiroshi; Marecek, James F. Tetrahedron Letters, 1982 , vol. 23, # 51 p. 5375 - 5376]
2, 4-Dinitrophenol as an activating reagent in a facile preparation of cyclic phosphate triesters
[Amigues, Eric J.; Migaud, Marie E. Tetrahedron Letters, 2004 , vol. 45, # 5 p. 1001 - 1004]
Hydrolysis of medium-ring phosphates. Mechanism of rate acceleration by an amino group
[Sharma, Ravinder K.; Vaidyanathaswamy, Ramamoorthy Journal of Organic Chemistry, 1982 , vol. 47, # 9 p. 1741 - 1745]