New synthetic protocols for the preparation of unsymmetrical bisindoles

…, AM Riahi, A Spannenberg, M Beller, MK Tse

Index: Kaiser, Hanns Martin; Lo, Wei Fun; Riahi, Abdol Majid; Spannenberg, Anke; Beller, Matthias; Tse, Man Kin Organic Letters, 2006 , vol. 8, # 25 p. 5761 - 5764

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Citation Number: 27

Abstract

Novel unsymmetrical bisindoles were synthesized by a solvent-free CC bond-formation reaction under mild conditions. Starting from aziridines or hydroxyl precursors, indoles have been used as C-nucleophiles to form new pharmacologically interesting bisindoles via an electrophilic aromatic substitution pathway in good to excellent yields.