Synlett

One-pot four-component reaction for the generation of pyrazoles and pyrimidines

JP Stonehouse, DS Chekmarev, NV Ivanova, S Lang…

Index: Stonehouse, Jeffrey P.; Chekmarev, Dmitriy S.; Ivanova, Natalya V.; Lang, Stuart; Pairaudeau, Garry; Smith, Neal; Stocks, Michael J.; Sviridov, Sergey I.; Utkina, Lyubov M. Synlett, 2008 , # 1 p. 100 - 104

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Citation Number: 17

Abstract

Abstract The palladium-catalysed four-component coupling of a halide, terminal alkyne, molybdenum hexacarbonyl and either a hydrazine or amidine has been shown to be an efficient method for the construction of highly substituted pyrazoles and pyrimidines, respectively, in a one-pot process.

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