Synlett

Effect of the Michael Acceptor in the asymmetric intramolecular Stetter reaction

MS Kerr, T Rovis

Index: Kerr, Mark S.; Rovis, Tomislav Synlett, 2003 , # 12 p. 1934 - 1936

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Citation Number: 19

Abstract

Abstract The effect of different Michael acceptors was evaluated in the catalytic asymmetric intramolecular Stetter reaction. Utilizing a readily prepared chiral triazolium salt as a nucleophilic carbene precursor, the reactivity and selectivity of substrates containing different electron-deficient double bonds was shown to vary significantly under identical reaction conditions.

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