Free-radical-mediated carbonylative cyclisation of alk-4-enyl halides leading to cyclopentanones

I Ryu, K Kusano, M Hasegawa, N Kannbe…

Index: Ryu, Ilhyong; Kusano, Kazuya; Hasegawa, Mitsuharu; Kambe, Nobuaki; Sonoda, Noboru Journal of the Chemical Society, Chemical Communications, 1991 , # 15 p. 1018 - 1019

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Citation Number: 20

Abstract

Modern synthetic chemistry requires a new efficient method- ology for the introduction of carbon monoxide into organic molecules. Free-radical carbonylation has considerable poten- tial and indeed we have previously demonstrated free-radical formylation starting with organic halides.1 The development of methods for construction of five-membered carbocycles largely owes its importance to the widespread occurrence of such substructures in natural and ...

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