Reactivity of aromatic o-hydroxy oximes. I. Synthesis and aminolysis of acylglycine esters of aromatic o-hydroxy oximes.

I Hayashi, K Ogihara, K Shimizu

Index: Hayashi, Ikuo; Ogihara, Keizo; Shimizu, Kiyoshi Bulletin of the Chemical Society of Japan, 1983 , vol. 56, # 8 p. 2432 - 2437

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Citation Number: 8

Abstract

Active esters (1) of glycine with o-hydroxybenzaldehyde oxime, o-hydroxyacetophenone oxime, o-hydroxybenzophenone oxime, and their 5-Cl and 5-NO 2 derivatives were prepared by several methods. For aminolysis with benzylamine, esters 1 show higher reactivity than similar esters containing no hydroxyl group in the ortho position. It is suggested that esters 1 forms an intramolecular hydrogen bond between the hydrogen of ...

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