Generalization of the Benzotriazole-Mediated Introduction of N-Substituents into Amides

AR Katritzky, AV Ignatchenko…

Index: Katritzky, Alan R.; Ignatchenko, Alexey V.; Lang, Hengyuan Journal of Organic Chemistry, 1995 , vol. 60, # 13 p. 4002 - 4005

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Citation Number: 28

Abstract

N-(Benzotriazol-1-ylmethyl) amides 2, easily available by condensation of BtCH2OH with amides, are used for the preparation of a variety of N-substituted amides such as the homoallyl, 1, 3-butadienyl, and 2, 2-diphenylcyclopropyl derivatives by displacement of the benzotriazole group under different conditions.

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