A new versatile synthesis of 4-substituted diaminopyridine derivatives
S Banerjee, B Voit, G Heinrich, F Böhme
Index: Banerjee, Sumela; Voit, Brigitte; Heinrich, Gert; Boehme, Frank Tetrahedron Letters, 2012 , vol. 53, # 17 p. 2236 - 2238
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Citation Number: 4
Abstract
A new convenient method for the synthesis of substituted 2, 6-diacetamido pyridines has been developed. It starts from 4-hydroxypyridine and comprises the introduction of the amino groups by the Chichibabin reaction. After several protection and deprotection steps 2, 6-diacetamido-4-hydroxy pyridine is obtained, which is regarded as a key compound for the synthesis of various substituted 2, 6-diacetamido pyridines. It is shown that the free ...
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