Pushing Back the Limits of Hydrosilylation: Unprecedented Catalytic Reduction of Organic Ureas to Formamidines

J Pouessel, O Jacquet, T Cantat

Index: Pouessel, Jacky; Jacquet, Olivier; Cantat, Thibault ChemCatChem, 2013 , vol. 5, # 12 p. 3552 - 3556

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Citation Number: 11

Abstract

Catalytic hydrosilylation of carbonyl functional groups is gaining an increasing interest in synthetic organic chemistry because it circumvents important limitations of the more classical hydrogenation or metal-hydride mediated reduction methodologies.[1] Indeed, hydrosilanes are practical reducing agents because they have a mild reduction potential and are less sensitive to moisture than LiAlH4, DIBAL, or NaBH4. Moreover, the slightly polar and ...