A new diarylheptanoid glycoside from the stem bark of Alnus hirsuta and protective effects of diarylheptanoid derivatives in human HepG2 cells

D Park, HJ Kim, SY Jung, CS Yook, C Jin…

Index: Park, Daae; Kim, Hyoung Ja; Jung, Seo Yun; Yook, Chang-Soo; Jin, Changbae; Lee, Yong Sup Chemical and Pharmaceutical Bulletin, 2010 , vol. 58, # 2 p. 238 - 241

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Citation Number: 28

Abstract

To search for secondary metabolites of Alnus hirsuta (Betulaceae), various chromatographic separations of the ethyl acetate soluble fraction of the stem bark of A. hirsuta led to the isolation of a new diarylheptanoid glycoside,(3R)-1, 7-bis-(4-dihydroxyphenyl)-3-heptanol 3- O-β-D-glucopyranosyl (1→ 3)-β-D-xylopyranoside (13) and twelve diarylheptanoid derivatives, namely, oregonin (1), rubranoside A (2), hirsutanonol 5-O-β-D- ...