Palladium??Catalyzed Suzuki Coupling with Terminal Alkynes–Application to the Synthesis of 2, 3??Disubstituted Benzo [b] furans

F Colobert, AS Castanet…

Index: Colobert, Francoise; Castanet, Anne-Sophie; Abillard, Olivier European Journal of Organic Chemistry, 2005 , # 15 p. 3334 - 3341

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Citation Number: 35

Abstract

Abstract The Suzuki coupling reaction between alkynylboronic esters (generated in situ from acetylenic derivatives) and aryl bromides, pyridyl bromides or vinyl bromides is reported. 5- endo-dig-iodocyclisation of o-alkynylanisoles, generated by this palladium-catalyzed Suzuki coupling reaction, was performed with N-iodosuccinimide (NIS) in the presence of BCl 3. 2- Substituted 3-iodobenzo [b] furans were synthesized and transformed into 2, 3- ...

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