Chiral Phosphino??and (Phosphinooxy)??Substituted N??Heterocyclic Carbene Ligands and Their Application in Iridium??Catalyzed Asymmetric Hydrogenation

S Nanchen, A Pfaltz

Index: Nanchen, Steve; Pfaltz, Andreas Helvetica Chimica Acta, 2006 , vol. 89, # 8 p. 1559 - 1573

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Citation Number: 42

Abstract

Abstract Enantiomerically pure iridium complexes with phosphino-and (phosphinooxy)- substituted N-heterocyclic carbene (NHC) ligands were synthesized. Investigation of their electronic properties showed a similar trans influence of the phosphino (or phosphinooxy) and the NHC units. The complexes were tested in iridium-catalyzed hydrogenation. While low conversions were observed with unfunctionalized olefins, the catalysts proved to be ...