The Journal of organic chemistry

Abc amino acids: design, synthesis, and properties of new photoelastic amino acids

RF Standaert, SB Park

Index: Standaert, Robert F.; Park, Seung Bum Journal of Organic Chemistry, 2006 , vol. 71, # 21 p. 7952 - 7966

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Citation Number: 32

Abstract

Photoisomerizable amino acids provide a direct avenue to the experimental manipulation of bioactive polypeptides, potentially allowing real-time, remote control of biological systems and enabling useful applications in nanobiotechnology. Herein, we report a new class of photoisomerizable amino acids intended to cause pronounced expansion and contraction in the polypeptide backbone, ie, to be photoelastic. These compounds, termed Abc amino ...