1, 3-Diphenylpyrazoles: synthesis and antiparasitic activities of azomethine derivatives
…, C Di Giorgio, P Timon-David, J Maldonado…
Index: Rathelot, Pascal; Azas, Nadine; El-Kashef, Hussein; Delmas, Florence; Di Giorgio, Carole; Timon-David, Pierre; Maldonado, Jose; Vanelle, Patrice European Journal of Medicinal Chemistry, 2002 , vol. 37, # 8 p. 671 - 679
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Citation Number: 135
Abstract
1, 3-Diphenylpyrazole-4-carboxaldehyde and 1-(4-nitrophenyl)-3-phenylpyrazole-4- carboxaldehyde were obtained from the appropriated phenylhydrazones via the Vilsmeier– Haack reaction. These two aldehydes were functionalized by various substituted anilines or substituted benzylamines. Antiparasitic activities of the corresponding azomethines were assessed. In the most cases, nitrated compounds were found to be more efficient than non ...
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