Potential Antiradiation Drugs. I. Amide, Hydroxamic Acid, and Hydrazine Derivatives of Mercapto Acids. Amino Thioacids1

ER Atkinson, GR Handrick, RJ Bruni…

Index: Atkinson,E.R. et al. Journal of Medicinal Chemistry, 1965 , vol. 8, p. 29 - 33

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Citation Number: 25

Abstract

The purpose of the work here described was to prepare pure organic compounds which might protect against the lethal effects of ionizing radiations2 When this work began it was known that aminoethanethiol, 3-amino-1-propanethiol, and a number of derivatives of these substances had some radioprotective action. It was suggested that compounds related to these substances, in which the state of oxidation of the carbon and nitrogen atoms in the ...