Synthesis

… -Catalyzed Cross-Coupling Reaction of (1-Ethoxy-1-alken-2-yl) boranes With ortho-Functionalized Iodoarenes. A Novel and Convenient Synthesis of Benzo-Fused …

M Satoh, N Miyaura, A Suzuki

Index: Satoh, Makoto; Miyaura, Norio; Suzuki, Akira Synthesis, 1987 , # 4 p. 373 - 377

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Citation Number: 40

Abstract

Ethoxy-l-alken-2-yl) boranes (6) were prepared by hydr0boration of 1-ethoxy-1-alkynes (4) with 1, 3, 2-benzodioxaborole (5). The hydroboration of 4 gave monohydroboration products regiospecifically; these were isolated as a single isomer in each case [for instance, 1I-I-NMR of 6b: 5= 7.06 ppm (s, vinylic H)]. The optimum conditions obtained in the previous work4 for the reaction I—> 3 were applied to the present cross-coupling reaction. Thus, the vinylic ...

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