Efficient Cu-catalyzed base-free C–S coupling under conventional and microwave heating. A simple access to S-heterocycles and sulfides

SM Soria-Castro, AB Peñéñory

Index: Soria-Castro, Silvia M.; Penenory, Alicia B. Beilstein Journal of Organic Chemistry, 2013 , vol. 9, p. 467 - 475

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Citation Number: 12

Abstract

Abstract S-aryl thioacetates can be prepared by reaction of inexpensive potassium thioacetate with both electron-rich and electron-poor aryl iodides under a base-free copper/ligand catalytic system. CuI as copper source affords S-aryl thioacetates in good to excellent yields, by using 1, 10-phenanthroline as a ligand in toluene at 100 C after 24 h. Under microwave irradiation the time was drastically reduced to 2 h. Both procedures are ...