Intramolecular nucleophilic addition of aryl bromides to ketones catalyzed by palladium

LG Quan, M Lamrani, Y Yamamoto

Index: Quan, Long Guo; Lamrani, Mouad; Yamamoto, Yoshinori Journal of the American Chemical Society, 2000 , vol. 122, # 19 p. 4827 - 4828

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Citation Number: 59

Abstract

Among many synthetically useful palladium-catalyzed transformations, 1 a reaction of uncommon pattern is the palladiumcatalyzed nucleophilic addition of organic halides to ketones and aldehydes, although such addition shown in eq 1 is the most frequently encountered reaction in traditional main-group metal chemistry. Nowadays, however, the reaction of this type is being opened in palladium chemistry; vinylpalladium halides, ...

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