Synthesis of indenes via aluminum chloride-promoted tandem Friedel–Crafts alkylation of arenes and cinnamaldehydes

H Kheira, P Li, J Xu

Index: Kheira, Haiouani; Li, Pingfan; Xu, Jiaxi Journal of Molecular Catalysis A: Chemical, 2014 , vol. 391, # 1 p. 168 - 174

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Citation Number: 6

Abstract

Abstract A series of substituted indenes were synthesized from arenes and cinnamaldehydes via aluminum chloride-promoted tandem Friedel–Crafts alkylation. The scope and limitation of the tandem reaction were explored. A plausible reaction mechanism is also discussed. This approach provides a convenient method for the synthesis of indene derivatives using a readily available and low cost Lewis acid and starting materials.