Sulbactam-d2 sodium

Modify Date: 2025-08-27 20:41:53

Sulbactam-d2 sodium Structure
Sulbactam-d2 sodium structure
Common Name Sulbactam-d2 sodium
CAS Number 948027-82-5 Molecular Weight 257.24
Density N/A Boiling Point N/A
Molecular Formula C8H8D2NNaO5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Sulbactam-d2 sodium


Sulbactam-d2 (sodium) is the deuterium labeled Sulbactam sodium[1]. Sulbactam (CP45899) sodium is a competitive, irreversible beta-lactamase inhibitor. Sulbactam sodium shows antimicrobial activity against multidrug-resistant (MDR) acinetobacter calcoaceticus--Acinetobacter baumannii (Acb) complex[2][3].

 Names

Name Sulbactam-d2 sodium

 Sulbactam-d2 sodium Biological Activity

Description Sulbactam-d2 (sodium) is the deuterium labeled Sulbactam sodium[1]. Sulbactam (CP45899) sodium is a competitive, irreversible beta-lactamase inhibitor. Sulbactam sodium shows antimicrobial activity against multidrug-resistant (MDR) acinetobacter calcoaceticus--Acinetobacter baumannii (Acb) complex[2][3].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Noguchi JK, et al. Sulbactam: a beta-lactamase inhibitor. Clin Pharm. 1988;7(1):37-51.  

[3]. Lin HS, et al. Sulbactam treatment for pneumonia involving multidrug-resistant Acinetobacter calcoaceticus-Acinetobacter baumannii complex. Infect Dis (Lond). 201547(6):370-378.  

[4]. Betrosian AP, et al. Ampicillin-sulbactam: an update on the use of parenteral and oral forms in bacterial infections. Expert Opin Drug Metab Toxicol. 20095(9):1099-1112.  

 Chemical & Physical Properties

Molecular Formula C8H8D2NNaO5S
Molecular Weight 257.24
InChIKey NKZMPZCWBSWAOX-RIUSHSMCSA-M
SMILES CC1(C)C(C(=O)[O-])N2C(=O)CC2S1(=O)=O.[Na+]
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