Duocarmycin SA intermediate-1
Modify Date: 2025-08-20 15:06:07
Duocarmycin SA intermediate-1 structure
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Common Name | Duocarmycin SA intermediate-1 | ||
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| CAS Number | 919535-07-2 | Molecular Weight | 678.51200 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C30H35IN2O8 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Duocarmycin SA intermediate-1Duocarmycin SA intermediate-1 is an intermediate in the synthesis of the antibiotic Duocarmycin SA (HY-12456). Duocarmycin SA intermediate-1 induces sequence-selective alkylation of double-stranded DNA and has synergistic, tumor-suppressive cytotoxicity with proton irradiation[1]. |
| Name | methyl (R)-7-benzyloxy-1-(tert-butoxycarbonyl)-5-(tert-butoxycarbonyl-(oxiran-2-ylmethyl)amino)-4-iodoindole-2-carboxylate |
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| Synonym | More Synonyms |
| Description | Duocarmycin SA intermediate-1 is an intermediate in the synthesis of the antibiotic Duocarmycin SA (HY-12456). Duocarmycin SA intermediate-1 induces sequence-selective alkylation of double-stranded DNA and has synergistic, tumor-suppressive cytotoxicity with proton irradiation[1]. |
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| Related Catalog | |
| References |
[1]. |
| Molecular Formula | C30H35IN2O8 |
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| Molecular Weight | 678.51200 |
| Exact Mass | 678.14400 |
| PSA | 108.83000 |
| LogP | 6.53500 |
| 7-Benzyloxy-5-(tert-butoxycarbonyl-(R)-1-oxiranylmethyl-amino)-4-iodo-indole-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester |