919535-07-2
919535-07-2 structure
- Name: Duocarmycin SA intermediate-1
- Chemical Name: methyl (R)-7-benzyloxy-1-(tert-butoxycarbonyl)-5-(tert-butoxycarbonyl-(oxiran-2-ylmethyl)amino)-4-iodoindole-2-carboxylate
- CAS Number: 919535-07-2
- Molecular Formula: C30H35IN2O8
- Molecular Weight: 678.51200
- Catalog: Research Areas Cancer
- Create Date: 2018-04-19 18:29:37
- Modify Date: 2025-08-20 15:06:07
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Duocarmycin SA intermediate-1 is an intermediate in the synthesis of the antibiotic Duocarmycin SA (HY-12456). Duocarmycin SA intermediate-1 induces sequence-selective alkylation of double-stranded DNA and has synergistic, tumor-suppressive cytotoxicity with proton irradiation[1].
| Name | methyl (R)-7-benzyloxy-1-(tert-butoxycarbonyl)-5-(tert-butoxycarbonyl-(oxiran-2-ylmethyl)amino)-4-iodoindole-2-carboxylate |
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| Synonyms | 7-Benzyloxy-5-(tert-butoxycarbonyl-(R)-1-oxiranylmethyl-amino)-4-iodo-indole-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester |
| Description | Duocarmycin SA intermediate-1 is an intermediate in the synthesis of the antibiotic Duocarmycin SA (HY-12456). Duocarmycin SA intermediate-1 induces sequence-selective alkylation of double-stranded DNA and has synergistic, tumor-suppressive cytotoxicity with proton irradiation[1]. |
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| Related Catalog | |
| References |
[1]. |
| Molecular Formula | C30H35IN2O8 |
|---|---|
| Molecular Weight | 678.51200 |
| Exact Mass | 678.14400 |
| PSA | 108.83000 |
| LogP | 6.53500 |