Gochnatiolide A

Modify Date: 2024-04-08 04:17:01

Gochnatiolide A Structure
Gochnatiolide A structure
Common Name Gochnatiolide A
CAS Number 87606-12-0 Molecular Weight 502.56
Density N/A Boiling Point N/A
Molecular Formula C30H30O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Gochnatiolide A


Gochnatiolide A is a dimeric sesquiterpene that can be found in Ainsliaea henryi. Gochnatiolide A exhibits antiproliferative activity against the kidney, melanoma, ovarian-resistant and glioma cell lines[1][2].

 Names

Name Gochnatiolide A

 Gochnatiolide A Biological Activity

Description Gochnatiolide A is a dimeric sesquiterpene that can be found in Ainsliaea henryi. Gochnatiolide A exhibits antiproliferative activity against the kidney, melanoma, ovarian-resistant and glioma cell lines[1][2].
Related Catalog
In Vitro Gochnatiolide A (0.25-250 μg/mL; 48 h) 抑制细胞生长,对 786.0,UACC-62,NCI-ADR/RES,U251,MCF-7,NCI-H460,HT-29,PC-3,OVCAR-3,VERO 和 K562 细胞的 TGI (总生长抑制) 值分别为 0.42,0.49,0.70,1.09,1.69,4.66,5.42,6.63,54.73,13.13 和 114.87 μg/mL[2] 。
References

[1]. Xiong HP, et, al. A dimeric sesquiterpene, gochnatiolide A. Acta Crystallogr Sect E Struct Rep Online. 2009 Oct 23;65(Pt 11):o2847.  

[2]. Strapasson RLB, et, al. Bioactivity-guided isolation of cytotoxic sesquiterpene lactones of Gochnatia polymorpha ssp. Floccose. Phytother Res. 2012 Jul;26(7):1053-6.  

 Chemical & Physical Properties

Molecular Formula C30H30O7
Molecular Weight 502.56
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