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87606-12-0

87606-12-0 structure

87606-12-0 structure

Name: Gochnatiolide A
Chemical Name: Gochnatiolide A
CAS Number: 87606-12-0
Molecular Formula: C₃₀H₃₀O₇
Molecular Weight: 502.56
Catalog: Research Areas Cancer
Create Date: 2023-04-17 13:04:40
Modify Date: 2024-04-08 04:17:01
Gochnatiolide A is a dimeric sesquiterpene that can be found in Ainsliaea henryi. Gochnatiolide A exhibits antiproliferative activity against the kidney, melanoma, ovarian-resistant and glioma cell lines[1][2].

Name	Gochnatiolide A

Description	Gochnatiolide A is a dimeric sesquiterpene that can be found in Ainsliaea henryi. Gochnatiolide A exhibits antiproliferative activity against the kidney, melanoma, ovarian-resistant and glioma cell lines[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	Gochnatiolide A (0.25-250 μg/mL; 48 h) 抑制细胞生长，对 786.0，UACC-62，NCI-ADR/RES，U251，MCF-7，NCI-H460，HT-29，PC-3，OVCAR-3，VERO 和 K562 细胞的 TGI (总生长抑制) 值分别为 0.42，0.49，0.70，1.09，1.69，4.66，5.42，6.63，54.73，13.13 和 114.87 μg/mL[2] 。
References	[1]. Xiong HP, et, al. A dimeric sesquiterpene, gochnatiolide A. Acta Crystallogr Sect E Struct Rep Online. 2009 Oct 23;65(Pt 11):o2847. [2]. Strapasson RLB, et, al. Bioactivity-guided isolation of cytotoxic sesquiterpene lactones of Gochnatia polymorpha ssp. Floccose. Phytother Res. 2012 Jul;26(7):1053-6.

Molecular Formula	C₃₀H₃₀O₇
Molecular Weight	502.56

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